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Updates to BMJ Best Practice topics

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 The following important updates have been made to BMJ Best Practice topics.

NICE recommends teplizumab to delay progression to stage 3 type 1 diabetes

Topic: Type 1 diabetes, Section: Management: emerging
The National Institute for Health and Care Excellence (NICE) in the UK now recommends teplizumab as an option for delaying the onset of stage 3 type 1 diabetes in adults and children aged 8 years and over with stage 2 type 1 diabetes. Previously, there were no treatments available to delay progression to stage 3 disease, and management was limited to monitoring, education, and psychosocial support.

European guidance lowers the bar for starting antiviral therapy in chronic HBV

Topic: Hepatitis B, Section: Management: approach
The European Association for the Study of the Liver (EASL) has published its updated clinical practice guideline on the management of hepatitis B virus (HBV) infection. Recommendations for when to start antiviral therapy have been updated to make sure patients who may benefit from antiviral therapy are not left untreated.

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